HXRefactored 2016

The conventional approach to weight loss, based on the calorie balance model, offers the simple advice, “eat less and move more.”  Unfortunately, few people can maintain weight loss over the long term through calorie restriction because the body fights back, with rising hunger and slowing metabolism. An alternative approach to treatment aims to target the underlying driver of weight gain – fat cells overstimulated to hoard too many calories – leading to weight loss with less struggle.